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First Look At An Enzyme Target For Antibacterial And Cancer Drugs

ScienceDaily (Dec. 28, 2007) — The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and replication, and is a prime target of antibacterial and anticancer drugs. Researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) at Berkeley have produced the first three-dimensional structural images of a DNA-bound Type II topoisomerase (topo II) that is responsible for untangling coiled strands of the chromosome during cell division.

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Hotspots Found For Chromosome Gene Swapping

ScienceDaily (Dec. 4, 2007) — Crossovers and double-strand DNA breaks do not occur randomly on yeast chromosomes during meiosis, but are greatly influenced by the proximity of the chromosome's telomere, according to research in the laboratory of Whitehead Fellow Andreas Hochwagen. This work may lead to a better understanding of developmental chromosome abnormalities and birth defects.

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Bathinda, November 30

The police here embarked on a multi-pronged strategy to curb the menace of drug abuse and prevent it from spreading its tentacles further, particularly amongst the youth. Working in that direction, the district police today organised a seminar on the theme Nasha Chado, Kohr Vado at Government Boys Senior Secondary School here.

Traders seek coins of small denominations
Barnala, November 30
Due to scarcity of coins of small denominations ranging from Re 1 to Rs 5, the shopkeepers as well as consumers are facing great difficulty. Expressing concern over this, local Beopar Mandal president Anil Kumar Nanna said that in the absence of coins of Re 1, Rs 2 and Rs 5, the shopkeepers had to give toffees, biscuits or matchboxes to customers.

Tree plantation campaign launched
Mansa, November 30
The Asra Lok Sewa Club, Mansa, has launched a tree plantation campaign along with other social service activities.


October 2006

No person in the U.S. shall, on the basis of sex be excluded from participation in, or denied the benefits of, or be subjected to discrimination under any educational program or activity receiving federal aid."

This latest initiative appears to have started when the US Department of Education announced that Title IX restrictions would not apply to experiments in grouping students on the basis of sex. I can find no reason why federal law is being waived for this except that many feel that Title IX, the gender equity law, applies only to how much money schools should be spending on school sports.

In a Cape Cod Times editorial today they took the position that it was a good idea. Well, they didn't really stick out their neck; they said it is worth considering.

My feeling is this: Schools should try single sex groupings it and see who it helps without tooting it all over the place as the answer. Results, in terms of test scores and emotional output should be studied.


Navigenics Launches With Preeminent Team of Advisers, Partners and ...

REDWOOD SHORES, Calif., Nov. 6 /PRNewswire/ -- Navigenics, Inc. launched officially today, naming a team of advisers and investors from leading communities in science, medicine, technology and public policy who are supporting the company.

Navigenics is a cutting-edge personalized, preventive health and wellness company, dedicated to improving health outcomes. The company will help people understand their genetic predisposition to disease and arm them with the information about what actions to take to help them stay healthy. Navigenics will accomplish this initially through use of a saliva-based, whole genome scan and analysis, matching an individual's DNA against scientifically and clinically vetted gene-disease correlation studies.

"The convergence of technology and biomedicine allows us to detect and act now to prevent the conditions that usually aren't revealed until later in life," said Navigenics board member David Brailer, M.D., Ph.D.


Fred Thompson has little cash to pursue late Iowa strategy

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Take two

He's got 12 tattoos: two Bugs Bunnies on his chest, one swallow on each hand, a rose on one arm and there's a lady on the other, and I think there's a tiger too. My favourite one is the Bugs Bunny.I see him every Saturday. I used to go swimming with him when we went to Cyprus on holiday but he's getting too old now. That's what Granny says.He was in the navy when he was younger, so he can't feel the cold. When he does the Loony Dook, he doesn't wear a top and he goes right out, swimming. But he can't go under the water because he's got asthma.I didn't really think he was mad, though – when I knew the money was going to charity, I thought it was good. I asked if I could do it and he said, "Don't do it, it's freezing." I had to persuade him to take me. My friends – Holly, Jacks, Becky and Paula – did it, so I decided to join in.My first time was .


Lupus gene finding prompts call for more DNA samples

Wellcome Trust researchers have identified a key gene involved in the disease Lupus, which affects around 50,000 people in the UK, mostly women. The lead researcher behind the study has called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease.

Lupus — or Systemic Lupus Erythematosus (SLE) — is an autoimmune disease which frequently causes skin rash, joint pains and malaise, but can also lead to inflammation of the kidneys and other internal organs. The risk of death in SLE is increased fivefold over that of the general population. However, because the symptoms are often non-specific, diagnosing the condition can be difficult. There is currently no cure for the disease, which can be triggered by viral infections, sunlight, trauma or stress, as well as puberty and childbirth.



 

 

 

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